MOTS-c 10 MG
Mitochondrial-Derived Research Peptide
MOTS-c is a 16-amino-acid mitochondrial-derived peptide studied for its potential role in cellular communication, energy metabolism, and the adaptive response to metabolic stress.
Current scientific research is investigating MOTS-c in areas including:
- Cellular energy metabolism
- AMPK-associated metabolic signaling
- Glucose homeostasis and insulin signaling
- Mitochondrial function and cellular stress adaptation
- Skeletal-muscle metabolism and exercise physiology
- Mechanisms associated with metabolic and cellular aging
MOTS-c is of particular scientific interest because mitochondrial-derived peptides may function as signaling molecules, allowing mitochondria to communicate with other cellular systems and influence metabolic and stress-response pathways.
Research Status
MOTS-c remains an investigational research compound. Research into its biological activity and potential applications is ongoing, and findings from preclinical or mechanistic studies should not be interpreted as established therapeutic benefits.
For laboratory research purposes only. Not for human consumption.
Sequence (1-letter):
MRWQEMGYIFYPRKLR
Sequence (3-letter):
Met–Arg–Trp–Gln–Glu–Met–Gly–Tyr–Ile–Phe–Tyr–Pro–Arg–Lys–Leu–Arg
So the chain is:
M → R → W → Q → E → M → G → Y → I → F → Y → P → R → K → L → R
MOTS-c is encoded within the mitochondrial 12S rRNA (MT-RNR1) region and is notable because it is a mitochondrial-derived peptide (MDP) rather than a conventional nuclear-encoded peptide.

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